What is the cause of Alzheimer's disease, Risk factors and prevention

What is the cause of Alzheimer's disease, Risk factors and prevention

Researchers have not been able to pinpoint exactly what causes Alzheimer's disease. However, certain risk factors can make you more likely to get this disease, such as age, genetics, lifestyle, environment, etc. Although some risk factors cannot be changed, they can still be affected. There are ways to reduce your risk of Alzheimer's.

We invite you to join Health Life For You to learn and discover about Alzheimer's disease - its causes, risk factors and ways to prevent it in this article!

What is the cause of Alzheimer's disease

Our brain is made up of billions of interconnected neurons. Many studies have shown that Alzheimer's disease occurs when the connections between these brain cells are lost. It can be caused by a buildup of proteins, the formation of abnormal structures called amyloid plaques and nerve fiber plexuses, which disrupt the functioning of brain cells and trigger symptoms.

As follows:

Amyloid plaques: When large chunks of protein, called beta-amyloid, build up around brain cells, they clump together into larger deposits called amyloid plaques that prevent the brain from sending and transmitting signals.

Formation of nerve fiber plexus: One type another protein called Tau that changes shape and organizes itself into structures called neurofibrillary tangles may also be responsible for Alzheimer's disease. These plexuses disrupt the nerve signal transport system and damage brain cells, and also degrade neurotransmitters. As a result, the signals from the brain are not transmitted properly.

Alzheimer's disease causes

The abnormal accumulation of these proteins eventually causes nerve cell damage and death, and brain tissue loss. Nerve cell death tends to cause shrinkage in the outer layer of the brain (the cerebral cortex) - an area that is important for memory, language and judgment. Over time, the disease progresses deep inside, affecting other functions and making symptoms worse. This is also characteristic of Alzheimer's disease.

The danger elements

Although the causes of Alzheimer's disease are still unclear, several factors may increase the risk of developing the disease. Scientists believe that for most people, Alzheimer's disease is caused by a combination of genetic, age, lifestyle and environmental factors that affect the brain over time.

As follows:


Age is not a direct cause of Alzheimer's disease, but it is the most important risk factor for the disease. Alzheimer's is not part of the body's normal aging process, but the older you get, the more likely you are to develop Alzheimer's disease. After age 65, the risk of Alzheimer's disease doubles every five years.

However, it's not just older people who can develop Alzheimer's disease. According to many studies, 1 in 20 people under the age of 65 will have this disease. This is called early-onset Alzheimer's disease and it can affect people as young as 40 years old.

causes of Alzheimer's disease due to age


Another common risk factor for Alzheimer's is genetics. People whose parents or siblings have Alzheimer's are more likely to develop the disease as they age. Scientists have identified mutations in three genes that can increase the production of amyloid plaques that damage the brain and lead to Alzheimer's disease.

However, cases where a genetic cause of Alzheimer's disease is quite rare, accounting for less than 1% of patients.

Down syndrome

Babies born with Down syndrome have a higher risk of developing Alzheimer's disease. This is because the genetic changes that cause Down syndrome can also lead to the formation of abnormal amyloid plaques that accumulate around brain cells. Alzheimer's disease also tends to start 10 to 20 years earlier in people with Down syndrome.

Severe head injury

Severe head trauma can also cause Alzheimer's disease. Several large studies have shown that people 50 years of age and older who have had a traumatic brain injury have a higher risk of dementia and Alzheimer's disease. The risk may be highest within the first 6 months to 2 years after a severe head injury.


Some studies show that there is a small difference in the risk of Alzheimer's disease between men and women. In general, more women get the disease because they generally live longer than men.

Mild cognitive impairment

Mild cognitive impairment (MCI) is a decline in memory or other thinking skills that is more than normal for a person's age. This condition is more likely to develop into dementia caused by Alzheimer's disease.

Other risk factors

Difficulty sleeping or not sleeping well causes Alzheimer's disease

Other lifestyle factors that may increase your risk of Alzheimer's include:

- Smoking or exposure to secondhand smoke.
- Excessive drinking.
- Difficulty falling asleep or staying asleep.
- Fat.
- Poorly controlled type 2 diabetes.
- High Blood Pressure.
- High cholesterol.
- Inactive.

Other risk factors may include:

- Hearing loss.
- Depression.
- Loneliness or social isolation.

Understanding the causes of Alzheimer's disease to know how to prevent

Because the cause of Alzheimer's disease is still unclear, there is no specific way to prevent the disease. However, a healthy lifestyle can help reduce your risk of disease or delay the onset of dementia, such as:

What's good for the heart is good for the brain. Please stop smoking and limit alcohol; Eat a healthy, balanced diet with plenty of fruits and vegetables each day.

Exercise for at least 150 minutes per week with consistent exercise. Physical activity increases blood flow to the brain.

Physical exercise to treat Alzheimer's

Maintain a healthy weight and lose weight if necessary. This is done through controlled eating and exercise.

Follow treatment guidelines to control high blood pressure, diabetes, and high cholesterol.

Maintain mental health. An active and healthy mind helps build brain cells, strengthening their connections. You should participate in social activities, play mind games and learn new things.

Regular health check-ups, especially for the elderly.

These measures not only bring benefits to heart health but also help improve mental health very well.

Hopefully through this article you have better understand the causes of Alzheimer's disease to have a more effective way to prevent and treat the disease !

Hopefully, through the above reading, you have a better understanding of loss of What is the cause of Alzheimer's disease, Risk factors and prevention as well as measures to help you solve memory problems. Stay tuned for new articles of Health Life For You to update useful information about loss of concentration, memory impairment.

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